Discover how Low Dose Naltrexone (LDN) is being used to support weight loss, reduce inflammation, manage autoimmune conditions, and improve overall wellness—available through in-person and virtual consultations at DOSE MedSpa.
What Is Low Dose Naltrexone (LDN)?
Originally approved by the FDA in the 1980s to treat opioid addiction in much higher doses (50mg+), Low Dose Naltrexone refers to the off-label use of naltrexone in doses ranging from 0.5mg to 4.5 mg. At these smaller doses, LDN doesn’t block opioids or cause withdrawal—it works very differently. It’s believed to help modulate the immune system, reduce chronic inflammation, and increase natural endorphin production.
This isn’t the stuff of hype—it’s backed by emerging clinical data and a growing body of anecdotal success from patients with chronic conditions who’ve found relief where other therapies failed.
How Does LDN Work?
LDN temporarily blocks opioid receptors, which paradoxically triggers your body to increase production of natural opioids (endorphins and enkephalins). These natural chemicals not only improve mood but also regulate the immune system and inflammation.
By increasing endorphins and modulating immune activity, LDN has shown promising results in:
-
Autoimmune diseases (Hashimoto’s, lupus, Crohn’s, MS)
-
Fibromyalgia and chronic pain
-
Depression and anxiety
-
Inflammatory skin conditions like psoriasis and eczema
-
Weight loss resistance due to inflammation or hormonal imbalance
LDN and Weight Loss: What’s the Connection?
This is where things get especially relevant at D.O.S.E.
Chronic inflammation, insulin resistance, and hormone imbalances are three major obstacles in sustainable weight loss. LDN may help reduce systemic inflammation and improve insulin sensitivity, making it a valuable adjunct in weight loss therapy, especially for patients who struggle with cravings or emotional eating linked to mood disorders.
We often pair LDN with semaglutide or tirzepatide protocols to address both the metabolic and neurochemical barriers to fat loss.
Is LDN Safe? What Are the Side Effects?
LDN is considered very safe, especially at the doses we prescribe. Most side effects are mild and temporary, including:
-
Vivid dreams (which usually subside)
-
Initial sleep disturbances
-
Mild headache or nausea
Because of its immune-modulating effects, it should be used with caution in patients taking immunosuppressive drugs. That’s why we require a thorough virtual consultation and lab review before prescribing.
Why We Offer LDN at D.O.S.E
As a MedSpa led by an Experienced Nurse Practitioner, we don’t believe in one-size-fits-all care. LDN represents a shift in medicine—toward personalized, root-cause-focused treatment that empowers the body to heal itself.
We offer virtual consultations throughout Illinois, so you can explore if LDN is right for you without ever stepping foot in our office.LDN
Ready to Learn If LDN Can Help You?
Schedule a virtual wellness consultation today to see if Low Dose Naltrexone fits into your customized health and weight loss plan.
👉 [Book Your Consultation today]
